Monthly Archives: July 2017

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Improving the development, monitoring and reporting of stroke rehabilitation research: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable

Abstract Recent reviews have demonstrated that the quality of stroke rehabilitation research has continued to improve over the last four decades but despite this progress, there are still many barriers in moving the field forward. Rigorous development, monitoring and complete reporting of interventions in stroke trials are essential in providing rehabilitation evidence that is robust, [...]

Standardized measurement of sensorimotor recovery in stroke trials: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable

Abstract Finding, testing and demonstrating efficacy of new treatments for stroke recovery is a multifaceted challenge. We believe that to advance the field, neurorehabilitation trials need a conceptually rigorous starting framework. An essential first step is to agree on definitions of sensorimotor recovery and on measures consistent with these definitions. Such standardization would allow pooling [...]

Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce

Abstract The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement in clinical trials and intervention development and reporting. This paper [...]

Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group

Abstract Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery. To download the free paper click here. Listen to a podcast with Dr Dale Corbett [...]

Biomarkers of stroke recovery: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable

Abstract The most difficult clinical questions in stroke rehabilitation are “What is this patient’s potential for recovery?” and “What is the best rehabilitation strategy for this person, given her/his clinical profile?” Without answers to these questions, clinicians struggle to make decisions regarding the content and focus of therapy, and researchers design studies that inadvertently mix [...]

Collaboration, post-stroke fatigue and functional magnetic resonance imaging

by Peter Goodin In science, collaboration is key. Collaboration leads to discussion, which can lead to new ideas, discoveries or breakthroughs. Collaboration has the potential to allow us to see our field through new eyes and make connections where we were unable to see them before. Recently, thanks to the collaboration between The Florey Institute [...]

Circuit class therapy is effective at improving walking after stroke and may reduce length of stay

by Coralie English This blog is based on the following publication: English C, Hillier SL, Lynch EA. Circuit class therapy for improving mobility after stroke. Cochrane Database of Systematic Reviews 2017, Issue 6. Art. No.: CD007513. DOI: 10.1002/14651858.CD007513.pub3. Roald Dahl wrote of his wife’s rehabilitation after stroke in 1965 Surely one hour a day is [...]

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Our Mission at CRE

  • Improve knowledge about recovery
  • Improve patient selection and rehabilitation research methods
  • Create training opportunities for clinicians and researchers
  • Provide a trials platform to help build clinical trials
  • Build a translation community to help drive future activity
  • Effectively implement proven cost effective interventions

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